ZARROUK A.
Publications
Articles répertoriés avec comité de lecture (Actes de conférences précisés)
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Protective effects of milk thistle (Sylibum marianum) seed oil and α-tocopherol against 7β-hydroxycholesterol-induced peroxisomal alterations in murine C2C12 myoblasts: Nutritional insights associated with the concept of pexotherapy
GHZAIEL I., ZARROUK A., ESSADEK S., MARTINE L., HAMMOUDA S., YAMMINE A., KSILA M., NURY T., MEDDEB W., TAHRI JOUTEY M., MIHOUBI W., CACCIA C., LEONI V., SAMADI M., ACARF N., ANDREOLETTI P., HAMMAMI S., GHRAIRI T., VEJUX A., HAMMAMI M., LIZARD G.
Steroids 183, 109032, (2022)
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Cytoprotective activities of representative nutrients from the Mediterranean diet and of Mediterranean oils against 7-ketocholesterol- and 7β-hydroxycholesterol-induced cytotoxicity: Application to age-related diseases and civilization diseases
REZIG L., GHZAIEL I., KSILA M., YAMMINE A., NURY T., ZARROUK A., SAMADI M., CHOUAIBI M., VEJUX A., LIZARD G.
Steroids 187, 109093, (2022)
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Sources of 7-ketocholesterol, metabolism and inactivation strategies: food and biomedical applications
GHZAIEL I., SASSI K., ZARROUK A., GHOSH S., DIAS I.H.K., NURY T., KSILA M., ESSADEK S., JOUTEY M.T., BRAHMI F., MIHOUBI W., RUP-JACQUES S., SAMADI M., REZIG L., MEZIANE S., GHRAIRI T., MASMOUDI-KOUKI O., HAMMAMI S., NASSER B., HAMMAMI M., WANG Y., GRIFFITHS W., VEJUX A., LIZARD G.
Redox Experimental Medecine 2022, (2022)
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Antioxidant Properties and Cytoprotective Effect of Pistacia lentiscus L. Seed Oil Against 7β‐Hydroxycholesterol‐Induced Toxicity in C2C12 Myoblasts: Reduction in Oxidative Stress, Mitochondrial and Peroxisomal Dysfunctions and Attenuation of Cell Death
GHZAIEL I., ZARROUK A., NURY T., LIBERGOLI M., FLORIO F., HAMMOUDA S., MENETRIER F., AVOSCAN L., YAMMINE A., SAMADI M., LATRUFFE N., BIRESSI S., LEVY D., BYDLOWSKI S.P., HAMMAMI S., VEJUX A., HAMMAMI M., LIZARD G.
Antioxidants 10, 1-39 (2021)
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7-Ketocholesterol: Effects on viral infections and hypothetical contribution in COVID-19
GHZAIEL I., SASSI K., ZARROUK A., NURY T., KSILA M., LEONI V., BOUHAOUALA-ZAHAR B., HAMMAMI S., HAMMAMI M., J. MACKRILL J., SAMADI M., GHRAIRI T., VEJUX A., LIZARD G.
The Journal of Steroid Biochemistry and Molecular Biology 212, 105939, 1-8 (2021)
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Attenuation of 7-ketocholesterol- and 7β-hydroxycholesterol-induced oxiapoptophagy by nutrients, synthetic molecules and oils: potential for the prevention of age-related diseases
NURY T., YAMMINE A., GHZAIEL I., SASSI K., ZARROUK A., BRAHMI F., SAMADI M., RUP-JACQUES S., VERVANDIER-FASSEUR D., PAIS DE BARROS J.P., BERGAS V., GHOSH S., MAJEED M., PANDE A., ATANASOV A., HAMMAMI S., HAMMAMI M., J. MACKRILL J., NASSER B., ANDREOLETTI P., CHERKAOUI MALKI M., VEJUX A., LIZARD G.
Ageing Research Reviews 101324, (2021)
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Prevention by Dietary Polyphenols (Resveratrol, Quercetin, Apigenin) Against 7-Ketocholesterol-Induced Oxiapoptophagy in Neuronal N2a Cells: Potential Interest for the Treatment of Neurodegenerative and Age-Related Diseases
YAMMINE A., ZARROUK A., NURY T., VEJUX A., LATRUFFE N., VERVANDIER-FASSEUR D., SAMADI M., J. MACKRILL J., GREIGE-GERGES H., AUEZOVA L., LIZARD G.
Cells 9, 11, 2346 (2020)
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Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrial alterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7β-hydroxycholesterol
SGHAIER R. , NURY T., LEONI V., CACCIA C., PAIS DE BARROS J.P., CHERIF A., VEJUX A., MOREAU T., LIMEM K., SAMADI M., J. MACKRILL J., SLAHEDDINE MASMOUDI A., ZARROUK A.
The Journal of Steroid Biochemistry and Molecular Biology 194, 1-20 (2019)
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Induction of a non-apoptotic mode of cell death associated with autophagic characteristics with steroidal maleic anhydrides and 7β-hydroxycholesterol on glioma cells
SASSI K., NURY T., ZARROUK A., SGHAIER R. , KHALAFI-NEZHAD A., VEJUX A., SAMADI M., BEN AISSA-FENNIRA F., LIZARD G.
The Journal of Steroid Biochemistry and Molecular Biology 191, 1-15 (2019)
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Biotin attenuation of oxidative stress, mitochondrial dysfunction, lipid metabolism alteration and 7β-hydroxycholesterol-induced cell death in 158N murine oligodendrocytes
SGHAIER R. , ZARROUK A., NURY T., BADREDDINE A., M. O'BRIEN N., J. MACKRILL J., VEJUX A., SAMADI M., NASSER B., CACCIA C., LEONI V., MOREAU T., CHERKAOUI MALKI M., SALHEDINE MASMOUDI A., LIZARD G.
Free Radical Research 53, 535-561 (2019)
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Modulation of Kv3.1b potassium channel level and intracellular potassium concentration in 158N murine oligodendrocytes and BV-2 murine microglial cells treated with 7-ketocholesterol, 24S-hydroxycholesterol or tetracosanoic acid
BEZINE M., MAATOUG S., BEN-KHALIFA R., DEBBABI M., ZARROUK A., WANG K., GRIFFITHS W., NURY T., SAMADI M., DE SEZE J., MOREAU T., KHARRAT R., EL-AYEB M., LIZARD G.
Biochimie 153, 56-69 (2018)
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Comparison of the effects of major fatty acids present in the Mediterranean diet (oleic acid, docosahexaenoic acid) and in hydrogenated oils (elaidic acid) on 7-ketocholesterol-induced oxiapoptophagy in microglial BV-2 cells
DEBBABI M., ZARROUK A., BEZINE M., MEDDEB W., NURY T., BADREDDINE A., KARYM El M., SGHAIER R. , BRETILLON L., GUYOT S., SAMADI M., CHERKAOUI MALKI M., NASSER B., MEJRI M., BEN-HAMMOU S., HAMMAMI M., LIZARD G.
Chemistry and Physics of Lipids 207, 151-170 (2017)
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Induction of oxiapoptophagy on 158N murine oligodendrocytes treated by 7- ketocholesterol, 7β-hydroxycholesterol, and 24(S)-hydroxycholesterol: protective effects of α-tocopherol and docosahexaenoic acid (DHA; C22:6 n-3).
NURY T., ZARROUK A., J. MACKRILL J., SAMADI M., DURAND P., RIEDINGER J.M., DORIA M., VEJUX A., LIMAGNE E., DELMAS D., PROST M., MOREAU T., HAMMAMI M., DELAGE-MOURROUX R., M. O'BRIEN N., LIZARD G.
Steroids 99, 194-203 (2015)
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Effects of cholesterol oxides on cell death induction and calcium increase 4 in human neuronal cells (SK-N-BE) and evaluation of the protective 5 effects of docosahexaenoic acid (DHA; C22:6 n-3)
ZARROUK A., NURY T., SAMADI M., O'CALLAGHAN Y., HAMMAMI M., M. O'BRIEN N., LIZARD G., J. MACKRILL J.
Steroids 99, 238-247 (2015)
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An expeditious synthesis of spinasterol and schottenol, two phytosterols present in argan oil and in cactus pear seed oil, and evaluation of their biological activities on cells of the central nervous system
BADREDDINE A., EL MOSTAFA K., ZARROUK A., NURY T., EL KHARRASSI Y., NASSER B., CHERKAOUI MALKI M., LIZARD G., SAMADI M.
Steroids 99, 119-124 (2015)
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Improved synthesis and in vitro evaluation of the cytotoxic profile of oxysterols oxidized at C4 (4a- and 4b-hydroxycholesterol) and C7 (7-ketocholesterol, 7a- and 7b hydroxycholesterol) on cells of the central nervous system
NURY T., SAMADI M., ZARROUK A., RIEDINGER J.M., LIZARD G.
European Journal of Medicinal Chemistry 70, 558-567 (2013)
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Biological activities of the LXRα and β agonist, 4β-hydroxycholesterol, and of its isomer, 4α hydroxycholesterol, on oligodendrocytes: Effects on cell growth and viability, oxidative and inflammatory status
NURY T., SAMADI M., VARIN A., LOPEZ T., ZARROUK A., BOUMHRAS M., RIEDINGER J.M., MASSON D., VEJUX A., LIZARD G.
Biochimie 95, 518-530 (2012)
Communications orales dans un congrès national ou international
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7β-hydroxycholesterol-induced oxidative stress, mitochondrial and peroxisomal dysfunctions: attenuation with Milk thistle seed oil
GHZAIEL I., YAMMINE A., NURY T., LIBERGOLI M., FLORIO F., HAMMOUDA S., HAMMAMI S., HAMMAMI M., BIRESSI S., EL MIDHAOUI A., SAMADI M., LEONI V., LIZARD G., ZARROUK A.
10th international symposium of the European Network on Oxysterols Research. (Via ZOOM) 16-17 September (2021)
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An expeditious synthesis of spinasterol and schotenol, two phytosterols present in argan oil and in cactus pear seed oil, and evaluation of their biological activities on cells of the central nervous system
BADREDDINE A., KARYM El M., EL KHARRASSI Y., ZARROUK A., NURY T., NASSER B., CHERKAOUI MALKI M., LIZARD G., SAMADI M.
4th ENOR Symposium Translational Research on Oxysterols Coimbra, Portugal, Septembre 18-19, 2014.
(2014)
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Evaluation of the protective effects of docosahexaenoic acid (DHA; C22:6 n-3) on 7-ketocholesterol-, 7β-hydroxycholesterol-, and 24S-hydroxycholesteroltreated 158N murine oligodendrocytes: attenuation of oxysterol-induced oxyapoptophagy and enhancement of
NURY T., ZARROUK A., J. MACKRILL J., SAMADI M., LIMAGNE E., RIEDINGER J.M., VEJUX A., DELMAS D., HAMMAMI M., M. O'BRIEN N., LIZARD G.
4th ENOR Symposium Translational Research on Oxysterols Coimbra, Portugal, Septembre 18-19, 2014.
(2014)
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Analysis of the effects of 7-ketocholesterol, 7α- and 7β-hydroxycholesterol, 6α and 6β-hydroxycholesterol, 4α and 4β-hydroxycholesterol, 24Shydroxycholesterol, and 27-hydroxycholesterol on calcium rise and accumulation, and cell death induction on human .
ZARROUK A., NURY T., SAMADI M., O'CALLAGHAN Y., VEJUX A., HAMMAMI M., M. O'BRIEN N., LIZARD G., J. MACKRILL J.
4th ENOR Symposium Translational Research on Oxysterols Coimbra, Portugal, Septembre 18-19, 2014.
(2014)
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Induction of a dual mode of cell death (autophagy and apoptosis) on 7-ketocholesterol-treated 158N murine oligodendrocytes
NURY T., DORIA M., ZARROUK A., BEGUE H., VEJUX A., SAMADI M., DELAGE-MOURROUX R., LIZARD G.
3rd European Network for Oxysterol Research (ENOR) Symposium, Swansea University - United Kingdom, Septembre 19-20, 2013. (2013)
Ouvrages et chapitres d'ouvrage
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Chapitre 21: Therapeutic Applications of Oxysterols and Derivatives in Age-Related Diseases, Infectious and Inflammatory Diseases, and Cancers
KSILA M., GHZAIEL I., SASSI K., ZARROUK A., LEONI V., POLI G., REZIG L., PIRES V., MEZIANE S., ATANASOV A., HAMMAMI S., HAMMAMI M., MASMOUDI-KOUKI O., HAMDI O., JOUANNY P., SAMADI M., VEJUX A., GHRAIRI T., LIZARD G.
Book: Implication of Oxysterols and Phytosterols in Aging and Human Diseases, Publisher: Springer, ISBN: 9783031438820 pp 379-400 (2023)
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Chapitre 19: In Vitro Evaluation of the Effects of 7-Ketocholesterol and 7β-Hydroxycholesterol on the Peroxisomal Status: Prevention of Peroxisomal Damages and Concept of Pexotherapy
GHZAIEL I., MAALOUL S., KSILA M., NAMSI A., YAMMINE A., DEBBABI M., BADREDDINE A., MEDDEB W., PIRES V., NURY T., MENETRIER F., AVOSCAN L., ZARROUK A., BAARINE M., MASMOUDI-KOUKI O., GHRAIRI T., ABDELLAOUI R., NASSER B., HAMMAMI S., HAMMAMI M., SAMADI M., VEJUX A., LIZARD G.
Book: Implication of Oxysterols and Phytosterols in Aging and Human Diseases, Publisher: Springer, ISBN: 9783031438820 pp 437-452 (2023)
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Chapitre 3: Chemical and Biochemical Features of Spinasterol and Schottenol
KHALLOUKI F., KSILA M., GHZAIEL I., ESSADEK S., TAHRI JOUTEY M., MAALOUL S., ZENNOUHI W., BENBACER L., HAJJI L., ZARROUK A., REZIG L., RUP-JACQUES S., ABDELLAOUI R., GHRAIRI T., MASMOUDI-KOUKI O., NASSER B., ANDREOLETTI P., CHERKAOUI MALKI M., SAMADI M., VEJUX A., LIZARD G.
Book: Implication of Oxysterols and Phytosterols in Aging and Human Diseases, Publisher: Springer, ISBN: 9783031438820 pp 45-55 (2023)