Nom:
SAMADI
Prénom:
Mohammad
Adresse mail:
Equipe:
Chimie Durable et Environnement
Catégorie membre:
Enseignants chercheurs
Statut:
Professeur
Téléphone:
03 72 74 91 42
SAMADI M.
Publications
Articles répertoriés avec comité de lecture (Actes de conférences précisés)
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Chemical synthesis and biochemical properties of cholestane-5α,6β-diol-3-sulfonate: A non-hydrolysable analogue of cholestane-5α,6β-diol-3β-sulfate
de MEDINA P., AYADI S., SOULES R., PAYRE B., RUP-JACQUES S., SILVENTE-POIROT S., SAMADI M., POIROT M.
The Journal of Steroid Biochemistry and Molecular Biology 234, 106396, 1-11 (2023) -
Two Argan Oil Phytosterols, Schottenol and Spinasterol, Attenuate Oxidative Stress and Restore LPS-Dysregulated Peroxisomal Functions in Acox1−/− and Wild-Type BV-2 Microglial Cells
ESSADEK S., GONDCAILLE C., SAVARY S., SAMADI M., VAMECQ J., LIZARD G., EL KEBBAJ R., LATRUFFE N., BENANI A., NASSER B., CHERKAOUI MALKI M., ANDREOLETTI P.
Antioxidants 12, 1-20 (2023) -
Protective effects of milk thistle (Sylibum marianum) seed oil and α-tocopherol against 7β-hydroxycholesterol-induced peroxisomal alterations in murine C2C12 myoblasts: Nutritional insights associated with the concept of pexotherapy
GHZAIEL I., ZARROUK A., ESSADEK S., MARTINE L., HAMMOUDA S., YAMMINE A., KSILA M., NURY T., MEDDEB W., TAHRI JOUTEY M., MIHOUBI W., CACCIA C., LEONI V., SAMADI M., ACARF N., ANDREOLETTI P., HAMMAMI S., GHRAIRI T., VEJUX A., HAMMAMI M., LIZARD G.
Steroids 183, 109032, (2022) -
Cytoprotective activities of representative nutrients from the Mediterranean diet and of Mediterranean oils against 7-ketocholesterol- and 7β-hydroxycholesterol-induced cytotoxicity: Application to age-related diseases and civilization diseases
REZIG L., GHZAIEL I., KSILA M., YAMMINE A., NURY T., ZARROUK A., SAMADI M., CHOUAIBI M., VEJUX A., LIZARD G.
Steroids 187, 109093, (2022) -
Sources of 7-ketocholesterol, metabolism and inactivation strategies: food and biomedical applications
GHZAIEL I., SASSI K., ZARROUK A., GHOSH S., DIAS I.H.K., NURY T., KSILA M., ESSADEK S., JOUTEY M.T., BRAHMI F., MIHOUBI W., RUP-JACQUES S., SAMADI M., REZIG L., MEZIANE S., GHRAIRI T., MASMOUDI-KOUKI O., HAMMAMI S., NASSER B., HAMMAMI M., WANG Y., GRIFFITHS W., VEJUX A., LIZARD G.
Redox Experimental Medecine 2022, (2022) -
Antioxidant Properties and Cytoprotective Effect of Pistacia lentiscus L. Seed Oil Against 7β‐Hydroxycholesterol‐Induced Toxicity in C2C12 Myoblasts: Reduction in Oxidative Stress, Mitochondrial and Peroxisomal Dysfunctions and Attenuation of Cell Death
GHZAIEL I., ZARROUK A., NURY T., LIBERGOLI M., FLORIO F., HAMMOUDA S., MENETRIER F., AVOSCAN L., YAMMINE A., SAMADI M., LATRUFFE N., BIRESSI S., LEVY D., BYDLOWSKI S.P., HAMMAMI S., VEJUX A., HAMMAMI M., LIZARD G.
Antioxidants 10, 1-39 (2021) -
7-Ketocholesterol: Effects on viral infections and hypothetical contribution in COVID-19
GHZAIEL I., SASSI K., ZARROUK A., NURY T., KSILA M., LEONI V., BOUHAOUALA-ZAHAR B., HAMMAMI S., HAMMAMI M., J. MACKRILL J., SAMADI M., GHRAIRI T., VEJUX A., LIZARD G.
The Journal of Steroid Biochemistry and Molecular Biology 212, 105939, 1-8 (2021) -
Attenuation of 7-ketocholesterol- and 7β-hydroxycholesterol-induced oxiapoptophagy by nutrients, synthetic molecules and oils: potential for the prevention of age-related diseases
NURY T., YAMMINE A., GHZAIEL I., SASSI K., ZARROUK A., BRAHMI F., SAMADI M., RUP-JACQUES S., VERVANDIER-FASSEUR D., PAIS DE BARROS J.P., BERGAS V., GHOSH S., MAJEED M., PANDE A., ATANASOV A., HAMMAMI S., HAMMAMI M., J. MACKRILL J., NASSER B., ANDREOLETTI P., CHERKAOUI MALKI M., VEJUX A., LIZARD G.
Ageing Research Reviews 101324, (2021) -
Prevention by Dietary Polyphenols (Resveratrol, Quercetin, Apigenin) Against 7-Ketocholesterol-Induced Oxiapoptophagy in Neuronal N2a Cells: Potential Interest for the Treatment of Neurodegenerative and Age-Related Diseases
YAMMINE A., ZARROUK A., NURY T., VEJUX A., LATRUFFE N., VERVANDIER-FASSEUR D., SAMADI M., J. MACKRILL J., GREIGE-GERGES H., AUEZOVA L., LIZARD G.
Cells 9, 11, 2346 (2020) -
Prevention of 7-Ketocholesterol-Induced Overproduction of Reactive Oxygen Species, Mitochondrial Dysfunction and Cell Death with Major Nutrients (Polyphenols, ω3 and ω9 Unsaturated Fatty Acids) of the Mediterranean Diet on N2a Neuronal Cells
YAMMINE A., NURY T., VEJUX A., LATRUFFE N., VERVANDIER-FASSEUR D., SAMADI M., GREIGE-GERGES H., AUEZOVA L., LIZARD G.
Molecules 25, 10, 2296 (2020) -
Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrial alterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7β-hydroxycholesterol
SGHAIER R. , NURY T., LEONI V., CACCIA C., PAIS DE BARROS J.P., CHERIF A., VEJUX A., MOREAU T., LIMEM K., SAMADI M., J. MACKRILL J., SLAHEDDINE MASMOUDI A., ZARROUK A.
The Journal of Steroid Biochemistry and Molecular Biology 194, 1-20 (2019) -
Induction of a non-apoptotic mode of cell death associated with autophagic characteristics with steroidal maleic anhydrides and 7β-hydroxycholesterol on glioma cells
SASSI K., NURY T., ZARROUK A., SGHAIER R. , KHALAFI-NEZHAD A., VEJUX A., SAMADI M., BEN AISSA-FENNIRA F., LIZARD G.
The Journal of Steroid Biochemistry and Molecular Biology 191, 1-15 (2019) -
Biotin attenuation of oxidative stress, mitochondrial dysfunction, lipid metabolism alteration and 7β-hydroxycholesterol-induced cell death in 158N murine oligodendrocytes
SGHAIER R. , ZARROUK A., NURY T., BADREDDINE A., M. O'BRIEN N., J. MACKRILL J., VEJUX A., SAMADI M., NASSER B., CACCIA C., LEONI V., MOREAU T., CHERKAOUI MALKI M., SALHEDINE MASMOUDI A., LIZARD G.
Free Radical Research 53, 535-561 (2019) -
Nanostructured Mesoporous Zinc‐Incorporated Copper Oxide (NMZI‐CuO): An Efficient and Reusable Nanocatalyst for the Synthesis of Esters through C−H Functionalization
MOADDELI A., ROUSTA M., SHEKOUHY M., KHALILI D., SAMADI M., KHALAFI-NEZHAD A.
Asian Journal of Organic Chemistry 8, 356-368 (2019) -
Modulation of Kv3.1b potassium channel level and intracellular potassium concentration in 158N murine oligodendrocytes and BV-2 murine microglial cells treated with 7-ketocholesterol, 24S-hydroxycholesterol or tetracosanoic acid
BEZINE M., MAATOUG S., BEN-KHALIFA R., DEBBABI M., ZARROUK A., WANG K., GRIFFITHS W., NURY T., SAMADI M., DE SEZE J., MOREAU T., KHARRAT R., EL-AYEB M., LIZARD G.
Biochimie 153, 56-69 (2018) -
Comparison of the effects of major fatty acids present in the Mediterranean diet (oleic acid, docosahexaenoic acid) and in hydrogenated oils (elaidic acid) on 7-ketocholesterol-induced oxiapoptophagy in microglial BV-2 cells
DEBBABI M., ZARROUK A., BEZINE M., MEDDEB W., NURY T., BADREDDINE A., KARYM El M., SGHAIER R. , BRETILLON L., GUYOT S., SAMADI M., CHERKAOUI MALKI M., NASSER B., MEJRI M., BEN-HAMMOU S., HAMMAMI M., LIZARD G.
Chemistry and Physics of Lipids 207, 151-170 (2017) -
Evidence of K+ homeostasis disruption in cellular dysfunction triggered by 7-ketocholesterol, 24S-hydroxycholesterol, and tetracosanoic acid (C24:0) in 158N murine oligodendrocytes
BEZINE M., DEBBABI M., NURY T., BEN-KHALIFA R., SAMADI M., CHERKAOUI MALKI M., VEJUX A., RAAS Q., DE SEZE J., MOREAU T., EL-AYEB M., LIZARD G.
(acte de conférence 6th ENOR) - Chemistry and Physics of Lipids - 6th ENOR Symposium Translational Research on Oxysterols. Paris, France, September 29-30, 2016 207, 135-150 (2017) -
Protecting group-free radical decarboxylation of bile acids: Synthesis of novel steroidal substituted maleic anhydrides and maleimides and evaluation of their cytotoxicity on C6 rat glioma cells
SAMADI M., NURY T., KHALAFI-NEZHAD A., LIZARD G.
Steroids 125, 124-130 (2017) -
Circulating oxysterol metabolites as potential new surrogate markers in patients with hormone receptor-positive breast cancer: Results of the OXYTAM study
DALENC F., IULIANO L., FILLERON T., ZERBINATI C., VOISIN M., ARELLANO C., CHATELUT E., MARQUET P., SAMADI M., ROCHE H., POIROT M., SILVENTE-POIROT S.
The Journal of Steroid Biochemistry and Molecular Biology 169, 210-218 (2017) -
Induction of oxiapoptophagy on 158N murine oligodendrocytes treated by 7- ketocholesterol, 7β-hydroxycholesterol, and 24(S)-hydroxycholesterol: protective effects of α-tocopherol and docosahexaenoic acid (DHA; C22:6 n-3).
NURY T., ZARROUK A., J. MACKRILL J., SAMADI M., DURAND P., RIEDINGER J.M., DORIA M., VEJUX A., LIMAGNE E., DELMAS D., PROST M., MOREAU T., HAMMAMI M., DELAGE-MOURROUX R., M. O'BRIEN N., LIZARD G.
Steroids 99, 194-203 (2015) -
Effects of cholesterol oxides on cell death induction and calcium increase 4 in human neuronal cells (SK-N-BE) and evaluation of the protective 5 effects of docosahexaenoic acid (DHA; C22:6 n-3)
ZARROUK A., NURY T., SAMADI M., O'CALLAGHAN Y., HAMMAMI M., M. O'BRIEN N., LIZARD G., J. MACKRILL J.
Steroids 99, 238-247 (2015) -
An expeditious synthesis of spinasterol and schottenol, two phytosterols present in argan oil and in cactus pear seed oil, and evaluation of their biological activities on cells of the central nervous system
BADREDDINE A., EL MOSTAFA K., ZARROUK A., NURY T., EL KHARRASSI Y., NASSER B., CHERKAOUI MALKI M., LIZARD G., SAMADI M.
Steroids 99, 119-124 (2015) -
Biological activities of Schottenol and Spinasterol, two natural phytosterols present in argan oil and in cactus pear seed oil, on murine miroglial BV2 cells
EL KHARRASSI Y., SAMADI M., LOPEZ T., NURY T., EL KEBBAJ R., ANDREOLETTI P., I EL HAJJ H., VAMECQ J., MOUSTAID K., LATRUFFE N., SAID EL KEBBAJ M., MASSON D., LIZARD G., NASSER B.
Biochemical and Biophysical Research Communications 446, 3, 798-804 (2014) -
Improved synthesis and in vitro evaluation of the cytotoxic profile of oxysterols oxidized at C4 (4a- and 4b-hydroxycholesterol) and C7 (7-ketocholesterol, 7a- and 7b hydroxycholesterol) on cells of the central nervous system
NURY T., SAMADI M., ZARROUK A., RIEDINGER J.M., LIZARD G.
European Journal of Medicinal Chemistry 70, 558-567 (2013) -
Biological activities of the LXRα and β agonist, 4β-hydroxycholesterol, and of its isomer, 4α hydroxycholesterol, on oligodendrocytes: Effects on cell growth and viability, oxidative and inflammatory status
NURY T., SAMADI M., VARIN A., LOPEZ T., ZARROUK A., BOUMHRAS M., RIEDINGER J.M., MASSON D., VEJUX A., LIZARD G.
Biochimie 95, 518-530 (2012) -
Contribution of cholesterol and oxysterols in the physiopathology of cataract: implication for the development of pharmacological treatments
VEJUX A., SAMADI M., LIZARD G.
Journal of Ophthalmology 2011, 471947, 1-6 (2011)
Brevets
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Fluoro-oxysterols positron tomography (PET) radiotracers
de MEDINA P., SAMADI M., COURBON F., SILVENTE-POIROT S., POIROT M.
European patent, EP23305003.8 (2023)
Communications orales dans un congrès national ou international
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Chemical synthesis and biological properties of cholestane-5α,6β-diol-3-sulfonate, a non-hydrolyzable analogue of cholestane-5α,6β-diol-3-Osulfate
de MEDINA P., SAMADI M., RUP-JACQUES S., SOULES R., SILVENTE-POIROT S., POIROT M.
11th international symposium of the European Network on Oxysterols Research. (Web Meeting), 16-17 September, 2022 (2022) -
7β-hydroxycholesterol-induced oxidative stress, mitochondrial and peroxisomal dysfunctions: attenuation with Milk thistle seed oil
GHZAIEL I., YAMMINE A., NURY T., LIBERGOLI M., FLORIO F., HAMMOUDA S., HAMMAMI S., HAMMAMI M., BIRESSI S., EL MIDHAOUI A., SAMADI M., LEONI V., LIZARD G., ZARROUK A.
10th international symposium of the European Network on Oxysterols Research. (Via ZOOM) 16-17 September (2021) -
Modulation of liver X receptor-beta (LXRß) expression by natural and synthetic steroids in rat C6 glioma model
SASSI K., NURY T., SAMADI M., BEN AISSA-FENNIRA F., LIZARD G.
BMAT 2018 – 2-4 nov 2018, Hammamet - Tunisie (2018) -
Characterization of the cytotoxic profile and evaluation of the expression of liver X receptor (lxr) on rat C6 glioma cells treated with natural and synthetic sterols
SASSI K., NURY T., SAMADI M., BEN AISSA-FENNIRA F., LIZARD G.
8th international symposium of the European Network on Oxysterols Research. Bologna, Italy, 20-21 September (2018) -
Evidence of K+ homeostasis disruption and potential involvement of Kv channels in cellular dysfunctions triggered by 7-ketocholesterol, 24S-hydroxycholesterol, and tetracosanoic acid on 158N oligodendrocytes
BEZINE M., DEBBABI M., NURY T., BEN-KHALIFA R., SAMADI M., EL-AYEB M., LIZARD G.
6th ENOR Symposium Translational Research on Oxysterols. Paris, France, September 29-30, 2016, Paris, France (2016) -
Evaluation of the protective effects of docosahexaenoic acid (DHA; C22:6 n-3) on 7-ketocholesterol-, 7β-hydroxycholesterol-, and 24S-hydroxycholesteroltreated 158N murine oligodendrocytes: attenuation of oxysterol-induced oxyapoptophagy and enhancement of
NURY T., ZARROUK A., J. MACKRILL J., SAMADI M., LIMAGNE E., RIEDINGER J.M., VEJUX A., DELMAS D., HAMMAMI M., M. O'BRIEN N., LIZARD G.
4th ENOR Symposium Translational Research on Oxysterols Coimbra, Portugal, Septembre 18-19, 2014. (2014) -
Analysis of the effects of 7-ketocholesterol, 7α- and 7β-hydroxycholesterol, 6α and 6β-hydroxycholesterol, 4α and 4β-hydroxycholesterol, 24Shydroxycholesterol, and 27-hydroxycholesterol on calcium rise and accumulation, and cell death induction on human .
ZARROUK A., NURY T., SAMADI M., O'CALLAGHAN Y., VEJUX A., HAMMAMI M., M. O'BRIEN N., LIZARD G., J. MACKRILL J.
4th ENOR Symposium Translational Research on Oxysterols Coimbra, Portugal, Septembre 18-19, 2014. (2014) -
An expeditious synthesis of spinasterol and schotenol, two phytosterols present in argan oil and in cactus pear seed oil, and evaluation of their biological activities on cells of the central nervous system
BADREDDINE A., KARYM El M., EL KHARRASSI Y., ZARROUK A., NURY T., NASSER B., CHERKAOUI MALKI M., LIZARD G., SAMADI M.
4th ENOR Symposium Translational Research on Oxysterols Coimbra, Portugal, Septembre 18-19, 2014. (2014) -
Induction of a dual mode of cell death (autophagy and apoptosis) on 7-ketocholesterol-treated 158N murine oligodendrocytes
NURY T., DORIA M., ZARROUK A., BEGUE H., VEJUX A., SAMADI M., DELAGE-MOURROUX R., LIZARD G.
3rd European Network for Oxysterol Research (ENOR) Symposium, Swansea University - United Kingdom, Septembre 19-20, 2013. (2013) -
Argan oil sterols as potential new LXR agonists
EL KHARRASSI Y., SAMADI M., LOPEZ T., EL KEBBAJ R., ANDREOLETTI P., MOUSTAID K., I EL HAJJ H., LATRUFFE N., VAMECQ J., SAID EL KEBBAJ M., MASSON D., SAVARY S., LIZARD G., NASSER B., CHERKAOUI MALKI M.
3rd European Network for Oxysterol Research (ENOR) Symposium, Swansea University - United Kingdom, Septembre 19-20, 2013. (2013) -
Short synthesis of 16α-hydroxy-5-cholestane-3,6-dione a novel cytotoxic marine oxysterol and 22 R- hydroxycholesterol
DENANCE M., GUYOT M., SAMADI M.
First European Network for Oxysterol Research (ENOR) Symposium, Sapienza University of Rome, Sep 22-24, 2011. (2011)
Ouvrages et chapitres d'ouvrage
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Chapitre 21: Therapeutic Applications of Oxysterols and Derivatives in Age-Related Diseases, Infectious and Inflammatory Diseases, and Cancers
KSILA M., GHZAIEL I., SASSI K., ZARROUK A., LEONI V., POLI G., REZIG L., PIRES V., MEZIANE S., ATANASOV A., HAMMAMI S., HAMMAMI M., MASMOUDI-KOUKI O., HAMDI O., JOUANNY P., SAMADI M., VEJUX A., GHRAIRI T., LIZARD G.
Book: Implication of Oxysterols and Phytosterols in Aging and Human Diseases, Publisher: Springer, ISBN: 9783031438820 pp 379-400 (2023) -
Chapitre 19: In Vitro Evaluation of the Effects of 7-Ketocholesterol and 7β-Hydroxycholesterol on the Peroxisomal Status: Prevention of Peroxisomal Damages and Concept of Pexotherapy
GHZAIEL I., MAALOUL S., KSILA M., NAMSI A., YAMMINE A., DEBBABI M., BADREDDINE A., MEDDEB W., PIRES V., NURY T., MENETRIER F., AVOSCAN L., ZARROUK A., BAARINE M., MASMOUDI-KOUKI O., GHRAIRI T., ABDELLAOUI R., NASSER B., HAMMAMI S., HAMMAMI M., SAMADI M., VEJUX A., LIZARD G.
Book: Implication of Oxysterols and Phytosterols in Aging and Human Diseases, Publisher: Springer, ISBN: 9783031438820 pp 437-452 (2023) -
Chapitre 3: Chemical and Biochemical Features of Spinasterol and Schottenol
KHALLOUKI F., KSILA M., GHZAIEL I., ESSADEK S., TAHRI JOUTEY M., MAALOUL S., ZENNOUHI W., BENBACER L., HAJJI L., ZARROUK A., REZIG L., RUP-JACQUES S., ABDELLAOUI R., GHRAIRI T., MASMOUDI-KOUKI O., NASSER B., ANDREOLETTI P., CHERKAOUI MALKI M., SAMADI M., VEJUX A., LIZARD G.
Book: Implication of Oxysterols and Phytosterols in Aging and Human Diseases, Publisher: Springer, ISBN: 9783031438820 pp 45-55 (2023) -
Chapter 6: Cholesterol Derivatives as Promising Anticancer Agents in Glioblastoma Metabolic Therapy
SASSI K., NURY T., SAMADI M., BEN AISSA-FENNIRA F., VEJUX A., LIZARD G.
Book: GLIOMAS. Exon Publications, Brisbane, Australia. Debinski W (Editor). ISBN: 978-0-6450017-4-7 (2021)